99 Lives Crowdfunding

Dear Feline Enthusiasts and friends,

99 Lives – every life counts! Please tweet, Instagram, and Facebook us to spread the news!

Help us give state-of-the-art health care to cats!

We are promoting a crowdfunding project called the “99 Lives Cat Genome Sequencing Initiative”. With research collaborators, we have already pooled together 50 domestic cats genomes and also the genomes of Black-footed cats and Pallas cats. We have already been successful with identifying two inherited blindnesses via this project and we are analyzing other traits. All participating researchers have access to the full genome set of data.

Please help us to promote this crowdfunding effort to raise additional funds so that we can sequence more genomes of both domestic and exotic felids. We hope to do eventually all breeds, species and sub-species / populations. Healthy individuals are as important as cats with health problems and interesting traits.

Please follow and spread this link, watch our video and explore the website to get more details and to make a contribution to the project!


Any donation is appreciate – many $10 donations can make a difference! Or just spread the news!

Donations are tax deductible and 97% goes to the research effort!

Best regards,
Dr. Leslie Lyons


  • og hjemmesiden indeholder også mange andre spændende ting end lige muligheden for at donere :slight_smile:

Kan vi danskere også trække det fra i skat Susanne? Bare af nysgerrighed, for det har jeg aldrig forsøgt at gøre, da jeg ikke kendte muligheden - men den er måske amerikansk?

Det er du simpelthen nødt til at spørge det danske skattevæsen om, jeg er ikke inde i de danske skatteregler :slight_smile:

Her er reglerne:

Fradrag for gaver til velgørende foreninger m.m.

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Du får fradrag for gaver til velgørende foreninger, fonde, stiftelser, institutioner og religiøse samfund, der er godkendt af SKAT.

[li]Du kan højst få fradrag for 15.000 kr. i 2015 (14.800 kr. i 2014).[/li]> [li]Du får automatisk dit fradrag, hvis du har givet foreningen dit cpr-nr.[/li]> [li]Der er ingen bagatelgrænse for fradraget.[/li]> [/ul]



Her er listen med ca. 1300 foreninger Skat.dk: C.A. Liste over godkendte foreninger



MT13-010 : 9 Lives Cat Genome Sequencing Initiative; $30,552 (Winn-funded study, final report)
Leslie Lyons, PhD, Barbara Gandolfi, PhD; University of Columbia-Missouri

The goal of the “9 Lives Cat Genome Sequencing Initiative” is multi-faceted and has been highly successful. Ten cats that had different heritable diseases and traits were whole genome sequenced to assist the determination of causal variants (mutations) for the conditions of interest. This project was the first to propose whole genome sequencing of cats beyond the one reference sequence that is available to the research community.
Using a strategy that combined several interesting traits into three different trios of cats, the project successfully identified DNA variants (mutations) that cause two different inherited blindness in Bengal and Persian cats, a variant likely causing bobbed tails and also a variant likely causing ear curl. The genetic tests for the blindness traits (available at the UC Davis Veterinary Genetics Laboratory and Langford Veterinary Services) have been released early while the investigators write and submit the manuscripts for scientific publication. By early release, breeders can take advantage of the tests more rapidly, preventing the production of blind cats while the scientific reports take time to get published.
Four additional traits have also been regionally localized to very narrow regions of the genomes and therefore, more testing is required to find the true causal DNA variants (mutations) for inherited hydrocephalus, Silver, brachycephaly, and LaPerm. Two genes for lymphosarcoma are being examined. Additional funding will be necessary to pursue these DNA variants (from new cat cases with mediastinal lymphoma to support DNA mutation confirmation).
In addition, the data from the nine cats (ten actually sequenced) launched the larger 99 Lives project. Researchers from over a dozen different institutions are using the data for their studies. The investigators have supported the identification of a lymphadenopathy in British shorthair cats and the University of Missouri-Columbia laboratory has identified causal variants (mutations) for a Devon Rex myopathy, commonly called spasticity, which is a model for human congenital myasthenic syndrome. They are also confirming DNA variants (mutations) causing stretchy, fragile skin called cutaneous asthenia, similar to Ehlers-Danlos syndrome in humans. The DNA variant (mutation) found from the 9 Lives and the now 99 Lives, which has 51 domestic cats included, can be used by the research community to design a high density DNA array, which would be fortuitous for complex disease studies, such as diabetes, FIP, and heart disease.
Wild cats are also benefiting from the project with discoveries for retinal degeneration in the Black-footed cat (Felis nigripes) and polycystic kidney disease in the Pallas cat (Otocolobus manul). Other wild cats, such as lions and tigers, are being added to the project to help focus on health problems in these felines as well. Eventually, all data will be freely released to the scientific community to support feline research in a variety of fields.